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Alan Aw

Postdoctoral Researcher
University of Pennsylvania
nalawanij (at) gmail.com


Publications

  1. A.J. Aw, J.P. Spence & Y.S. Song (2024). A simple and flexible test of sample exchangeability with applications to statistical genomics. Annals of Applied Statistics 18 (1):858-881. DOI: 10.1214/23-AOAS1817 (Software: flintyR and flintyPy, Code and Data, Tutorials)
  2. A.J. Aw, L.C. Jin, N.M. Ioannidis & Y.S. Song (2023). The impact of stability considerations on genetic fine-mapping. eLife Reviewed Preprint. DOI: 10.7554/eLife.88039.1 (Shiny App, Code and Data)
  3. T.C. Zeng, A.J. Aw & M.W. Feldman (2018). Cultural hitchhiking and competition between patrilineal kin groups explain the post-Neolithic Y-chromosome bottleneck. Nature Communications 9 (1): article no. 2077. DOI: 10.1038/s41467-018-04375-6 (Code and Data)
  4. A.J. Aw & N.A. Rosenberg (2018). Bounding measures of genetic similarity and diversity using majorization. Journal of Mathematical Biology 77 (3): 711-737. DOI: 10.1007/s00285-018-1226-x
  5. A.J. Aw & C.Y. Ku (2015). The covering radius problem for sets of 1-factors of the complete uniform hypergraphs. Discrete Mathematics 338 (6):P 875-884. DOI: 10.1016/j.disc.2015.01.014
  6. A.J. Aw (2014). The multicovering radius problem for some types of discrete structures. Designs, Codes and Cryptography 72 (2): 195-209. DOI: 10.1007/s10623-012-9755-6
  7. A.J. Aw (2012). The Turán number and probabilistic combinatorics. The American Mathematical Monthly 119 (6): 510-513. DOI: 10.4169/amer.math.monthly.119.06.510

Preprints / Under Review

  1. A.J. Aw, J.F. McRae, E. Rahmani & Y.S. Song (2024+). Highly parameterized polygenic scores tend to overfit to population stratification via random effects. bioRXiv preprint. DOI: 10.1101/2024.01.27.577589 (Code and Data, Dashboard)
  2. G. Benegas, C. Albors, A.J. Aw, C. Ye, Y.S. Song (2023+). GPN-MSA: an alignment-based DNA language model for genome-wide variant effect prediction. bioRXiv preprint. DOI: 10.1101/2023.10.10.561776 (Code and Data)

In Preparation

  1. A.J. Aw, Penn Medicine Biobank, I.N. Mathieson (2024+). Using partial polygenic scores to detect gene-by-ancestry interactions in recently admixed populations.
  2. F. Zhou, A.J. Aw, D. Erdmann-Pham, J. Fischer, Y.S. Song (2024+). General non-parametric tests for differential gene expression analysis.
  3. J.V. Moreno-Mayar, A.J. Aw, Y. Deng, …, G. Kroonen, P. Grebenyuk, D. Meltzer, Y.S. Song, E. Willerslev (2024+). Historical ancient genomics shed light on dynamic Holocene origins of Indigenous Siberians and their languages.

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